Genito-urinary cancers include the kidneys, ureters (which carry urine from the kidneys to the bladder), bladder, testicles, and hormone resistant prostate cancer. For patients on this chemotherapy combination, the PET scan was able to identify who went on to have a more favourable outcome, including using newer indicators such as the metabolic volume of the tumor, which software techniques have only permitted the calculation of in the past few years. The second generation Discovery PET/CT scanner at INITIO includes the ability to calculate the metabolic volume of a tumor, and we routinely report these emerging biomarkers to our referring physicians.